Enteric coating of tablets containing an amorphous solid dispersion of an enteric polymer and a weakly basic drug: A strategy to enhance in vitro release

Recent work has highlighted that amorphous solid dispersions (ASDs) containing delamanid (DLM) and an enteric polymer, hypromellose phthalate (HPMCP), appear to be susceptible to crystallization during immersion in simulated gastric fluids. The goal of this study was to minimize contact of the ASD p...

Descripción completa

Detalles Bibliográficos
Autores principales: Nguyen, Hanh Thuy, Van Duong, Tu, Taylor, Lynne S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier/North-Holland Biomedical Press 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10390825/
https://www.ncbi.nlm.nih.gov/pubmed/37311499
http://dx.doi.org/10.1016/j.ijpharm.2023.123139

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10390825/
https://www.ncbi.nlm.nih.gov/pubmed/37311499
http://dx.doi.org/10.1016/j.ijpharm.2023.123139

Ejemplares similares