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Nanostructured lipid carriers containing benznidazole: physicochemical, biopharmaceutical and cellular in vitro studies

Chagas disease is a neglected endemic disease prevalent in Latin American countries, affecting around 8 million people. The first-line treatment, benznidazole (BNZ), is effective in the acute stage of the disease but has limited efficacy in the chronic stage, possibly because current treatment regim...

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Detalles Bibliográficos
Autores principales: Muraca, Giuliana, Ruiz, María Esperanza, Gambaro, Rocío C, Scioli-Montoto, Sebastián, Sbaraglini, María Laura, Padula, Gisel, Cisneros, José Sebastián, Chain, Cecilia Yamil, Álvarez, Vera A, Huck-Iriart, Cristián, Castro, Guillermo R, Piñero, María Belén, Marchetto, Matias Ildebrando, Alba Soto, Catalina, Islan, Germán A, Talevi, Alan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10390827/
https://www.ncbi.nlm.nih.gov/pubmed/37533841
http://dx.doi.org/10.3762/bjnano.14.66