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Involvement of 5-HT(1A) receptors of the thalamic descending pathway in the analgesic effect of intramuscular heating-needle stimulation in a rat model of lumbar disc herniation

BACKGROUND: Intramuscular (IM) heating-needle therapy, a non-painful thermal therapy, has been found to exert an analgesic effect via the thalamic ventromedial (VM) nucleus, solely by reducing the triggering threshold for descending inhibition; this could be modulated by intracephalic 5-hydroxytrypt...

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Detalles Bibliográficos
Autores principales: Ma, Yuhong, Zhan, Yijun, Pei, Jian, Ye, Gang, Chen, Yaoxin, Zhu, Wenyan, Shen, Haiyue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10390831/
https://www.ncbi.nlm.nih.gov/pubmed/37534035
http://dx.doi.org/10.3389/fnins.2023.1222286