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ZEB1 Is Regulated by K811 Acetylation to Promote Stability, NuRD Complex Interactions, EMT, and NSCLC Metastasis

Epithelial-to-mesenchymal transition results in loss of specialized epithelial cell contacts and acquisition of mesenchymal invasive capacity. The transcription repressor zinc finger E-box-binding homeobox 1 (ZEB1) binds to E-boxes of gene promoter regions to suppress the expression of epithelial ge...

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Detalles Bibliográficos
Autores principales: Perez-Oquendo, Mabel, Manshouri, Roxsan, Tian, Yanhua, Fradette, Jared J., Rodriguez, B. Leticia, Kundu, Samrat T., Gibbons, Don L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10390859/
http://dx.doi.org/10.1158/1541-7786.MCR-22-0503