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PERK signaling promotes mitochondrial elongation by remodeling membrane phosphatidic acid

Endoplasmic reticulum (ER) stress and mitochondrial dysfunction are linked in the onset and pathogenesis of numerous diseases. This has led to considerable interest in defining the mechanisms responsible for regulating mitochondria during ER stress. The PERK signaling arm of the unfolded protein res...

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Detalles Bibliográficos
Autores principales: Perea, Valerie, Cole, Christian, Lebeau, Justine, Dolina, Vivian, Baron, Kelsey R, Madhavan, Aparajita, Kelly, Jeffery W, Grotjahn, Danielle A, Wiseman, R Luke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10390871/
https://www.ncbi.nlm.nih.gov/pubmed/37306086
http://dx.doi.org/10.15252/embj.2023113908