Methylnaltrexone Treatment for Opioid-Induced Constipation in Patients with and without Cancer: Effect of Initial Dose

PURPOSE: Opioid-induced constipation (OIC) is a common side effect of opioid therapy. Methylnaltrexone (MNTX) is a selective, peripherally acting μ-opioid receptor antagonist, with demonstrated efficacy in treating OIC. We pooled results from MNTX clinical trials to compare responses to an initial d...

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Detalles Bibliográficos
Autores principales: Chamberlain, Bruce H, Rhiner, Michelle, Slatkin, Neal E, Stambler, Nancy, Israel, Robert J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2023
Materias:
Clinical Trial Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10391063/
https://www.ncbi.nlm.nih.gov/pubmed/37533563
http://dx.doi.org/10.2147/JPR.S405825

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10391063/
https://www.ncbi.nlm.nih.gov/pubmed/37533563
http://dx.doi.org/10.2147/JPR.S405825

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