Oxidative Phosphorylation Fueled by Fatty Acid Oxidation Sensitizes Leukemic Stem Cells to Cold

Dependency on mitochondrial oxidative phosphorylation (OxPhos) is a potential weakness for leukemic stem cells (LSC) that can be exploited for therapeutic purposes. Fatty acid oxidation (FAO) is a crucial OxPhos-fueling catabolic pathway for some acute myeloid leukemia (AML) cells, particularly chem...

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Detalles Bibliográficos
Autores principales: Griessinger, Emmanuel, Pereira-Martins, Diego, Nebout, Marielle, Bosc, Claudie, Saland, Estelle, Boet, Emiline, Sahal, Ambrine, Chiche, Johanna, Debayle, Delphine, Fleuriot, Lucile, Pruis, Maurien, De Mas, Véronique, Vergez, François, Récher, Christian, Huls, Gerwin, Sarry, Jean-Emmanuel, Schuringa, Jan Jacob, Peyron, Jean-François
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2023
Materias:
Priority Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10391327/
https://www.ncbi.nlm.nih.gov/pubmed/37272750
http://dx.doi.org/10.1158/0008-5472.CAN-23-1006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10391327/
https://www.ncbi.nlm.nih.gov/pubmed/37272750
http://dx.doi.org/10.1158/0008-5472.CAN-23-1006

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