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Single-cell deep phenotyping of cytokine release unmasks stimulation-specific biological signatures and distinct secretion dynamics

Cytokines are important mediators of the immune system, and their secretion level needs to be carefully regulated, as an unbalanced activity may lead to cytokine release syndromes. Dysregulation can be induced by various factors, including immunotherapies. Therefore, the need for risk assessment dur...

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Detalles Bibliográficos
Autores principales: Portmann, Kevin, Linder, Aline, Oelgarth, Nicole, Eyer, Klaus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10391336/
https://www.ncbi.nlm.nih.gov/pubmed/37533643
http://dx.doi.org/10.1016/j.crmeth.2023.100502