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Single-cell deep phenotyping of cytokine release unmasks stimulation-specific biological signatures and distinct secretion dynamics
Cytokines are important mediators of the immune system, and their secretion level needs to be carefully regulated, as an unbalanced activity may lead to cytokine release syndromes. Dysregulation can be induced by various factors, including immunotherapies. Therefore, the need for risk assessment dur...
Autores principales: | Portmann, Kevin, Linder, Aline, Oelgarth, Nicole, Eyer, Klaus |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10391336/ https://www.ncbi.nlm.nih.gov/pubmed/37533643 http://dx.doi.org/10.1016/j.crmeth.2023.100502 |
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