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Characterization of cell-fate decision landscapes by estimating transcription factor dynamics

Time-specific modulation of gene expression during differentiation by transcription factors promotes cell diversity. However, estimating their dynamic regulatory activity at the single-cell level and in a high-throughput manner remains challenging. We present FateCompass, an integrative approach tha...

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Detalles Bibliográficos
Autores principales: Jiménez, Sara, Schreiber, Valérie, Mercier, Reuben, Gradwohl, Gérard, Molina, Nacho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10391345/
https://www.ncbi.nlm.nih.gov/pubmed/37533652
http://dx.doi.org/10.1016/j.crmeth.2023.100512