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Characterization of cell-fate decision landscapes by estimating transcription factor dynamics
Time-specific modulation of gene expression during differentiation by transcription factors promotes cell diversity. However, estimating their dynamic regulatory activity at the single-cell level and in a high-throughput manner remains challenging. We present FateCompass, an integrative approach tha...
Autores principales: | Jiménez, Sara, Schreiber, Valérie, Mercier, Reuben, Gradwohl, Gérard, Molina, Nacho |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10391345/ https://www.ncbi.nlm.nih.gov/pubmed/37533652 http://dx.doi.org/10.1016/j.crmeth.2023.100512 |
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