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Profiling of idiopathic macular hole vitreous proteome identifies the role of extracellular matrix remodelling, epithelial–mesenchymal transformation and unfolded protein-response pathways

PURPOSE: To analyze and describe the proteome of the vitreous humour in eyes with idiopathic macular holes. METHODS: We performed mass spectrometry (MS)-based label-free quantitative analysis of the vitreous proteome of idiopathic macular hole (IMH) and control donor vitreous. Comparative quantifica...

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Detalles Bibliográficos
Autores principales: Sen, Sagnik, Udaya, Prithviraj, Maheshwari, Jayapal J, Ramasamy, Kim, Kannan, Naresh B, Dharmalingam, Kuppamuthu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10391365/
https://www.ncbi.nlm.nih.gov/pubmed/37203077
http://dx.doi.org/10.4103/ijo.IJO_2068_22