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Combined Donepezil with Astaxanthin via Nanostructured Lipid Carriers Effective Delivery to Brain for Alzheimer’s Disease in Rat Model

INTRODUCTION: Donepezil (DPL), a specific acetylcholinesterase inhibitor, is used as a first-line treatment to improve cognitive deficits in Alzheimer’s disease (AD) and it might have a disease modifying effect. Astaxanthin (AST) is a natural potent antioxidant with neuroprotective, anti-amyloidogen...

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Detalles Bibliográficos
Autores principales: Shehata, Mustafa K, Ismail, Assem A, Kamel, Maher A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10391537/
https://www.ncbi.nlm.nih.gov/pubmed/37534058
http://dx.doi.org/10.2147/IJN.S417928