Preserving extracellular space for high-quality optical and ultrastructural studies of whole mammalian brains

Analysis of brain structure, connectivity, and molecular diversity relies on effective tissue fixation. Conventional tissue fixation causes extracellular space (ECS) loss, complicating the segmentation of cellular objects from electron microscopy datasets. Previous techniques for preserving ECS in m...

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Detalles Bibliográficos
Autores principales: Lu, Xiaotang, Han, Xiaomeng, Meirovitch, Yaron, Sjöstedt, Evelina, Schalek, Richard L., Lichtman, Jeff W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10391564/
https://www.ncbi.nlm.nih.gov/pubmed/37533653
http://dx.doi.org/10.1016/j.crmeth.2023.100520

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10391564/
https://www.ncbi.nlm.nih.gov/pubmed/37533653
http://dx.doi.org/10.1016/j.crmeth.2023.100520

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