Targeted insertion and reporter transgene activity at a gene safe harbor of the human blood fluke, Schistosoma mansoni

The identification and characterization of genomic safe harbor sites (GSHs) can facilitate consistent transgene activity with minimal disruption to the host cell genome. We combined computational genome annotation and chromatin structure analysis to predict the location of four GSHs in the human blo...

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Detalles Bibliográficos
Autores principales: Ittiprasert, Wannaporn, Moescheid, Max F., Chaparro, Cristian, Mann, Victoria H., Quack, Thomas, Rodpai, Rutchanee, Miller, André, Wisitpongpun, Prapakorn, Buakaew, Watunyoo, Mentink-Kane, Margaret, Schmid, Sarah, Popratiloff, Anastas, Grevelding, Christoph G., Grunau, Christoph, Brindley, Paul J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10391569/
https://www.ncbi.nlm.nih.gov/pubmed/37533651
http://dx.doi.org/10.1016/j.crmeth.2023.100535

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10391569/
https://www.ncbi.nlm.nih.gov/pubmed/37533651
http://dx.doi.org/10.1016/j.crmeth.2023.100535

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