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Heterologous Expression of the Formicamycin Biosynthetic Gene Cluster Unveils Glycosylated Fasamycin Congeners

[Image: see text] Formicamycins and their biosynthetic intermediates the fasamycins are polyketide antibiotics produced by Streptomyces formicae KY5 from a pathway encoded by the for biosynthetic gene cluster. In this work the ability of Streptomyces coelicolor M1146 and the ability of Saccharopolys...

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Detalles Bibliográficos
Autores principales: McDonald, Hannah P., Alford, Abigail, Devine, Rebecca, Hems, Edward S., Nepogodiev, Sergey A., Arnold, Corinne J., Rejzek, Martin, Stanley-Smith, Anna, Holmes, Neil A., Hutchings, Matthew I., Wilkinson, Barrie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society and American Society of Pharmacognosy 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10391614/
https://www.ncbi.nlm.nih.gov/pubmed/37327570
http://dx.doi.org/10.1021/acs.jnatprod.3c00052