N-Terminal Cysteine Bioconjugation with (2-Cyanamidophenyl)boronic Acids Enables the Direct Formation of Benzodiazaborines on Peptides

[Image: see text] Benzodiazaborines (BDABs) have emerged as a valuable tool to produce stable and functional bioconjugates via a click-type transformation. However, the current available methods to install them on peptides lack bioorthogonality, limiting their applications. Here, we report a strateg...

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Detalles Bibliográficos
Autores principales: Padanha, Rita, Cavadas, Rafaela A. N., Merino, Pedro, António, João P. M., Gois, Pedro M. P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10391619/
https://www.ncbi.nlm.nih.gov/pubmed/37466099
http://dx.doi.org/10.1021/acs.orglett.3c01835

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10391619/
https://www.ncbi.nlm.nih.gov/pubmed/37466099
http://dx.doi.org/10.1021/acs.orglett.3c01835

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