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Unmasking the True Identity of Rapamycin’s Minor Conformer
[Image: see text] Rapamycin, a well-known macrocyclic natural product with myriad biological activities, has been the subject of intense study since its first isolation and characterization over five decades ago. Rapamycin has been found to adopt a single conformation in the solid state (both when p...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society and American Society of Pharmacognosy
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10391620/ https://www.ncbi.nlm.nih.gov/pubmed/37432113 http://dx.doi.org/10.1021/acs.jnatprod.3c00421 |