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Unmasking the True Identity of Rapamycin’s Minor Conformer

[Image: see text] Rapamycin, a well-known macrocyclic natural product with myriad biological activities, has been the subject of intense study since its first isolation and characterization over five decades ago. Rapamycin has been found to adopt a single conformation in the solid state (both when p...

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Detalles Bibliográficos
Autores principales: Crull, Emily B., Jain, Ajay N., Hawkins, Paul C. D., Cleves, Ann E., Graziani, Edmund I., Williamson, R. Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society and American Society of Pharmacognosy 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10391620/
https://www.ncbi.nlm.nih.gov/pubmed/37432113
http://dx.doi.org/10.1021/acs.jnatprod.3c00421