Cargando…

Bioinspired Synthesis of Platensimycin from Natural ent-Kaurenoic Acids

[Image: see text] The biomimetic formal synthesis of the antibiotic platensimycin for the treatment of infection by multidrug-resistant bacteria was accomplished starting from either ent-kaurenoic acid or grandiflorenic acid, each of which is a natural compound available in multigram scale from its...

Descripción completa

Detalles Bibliográficos
Autores principales: Pérez, Álvaro, Quílez del Moral, José F., Galisteo, Alberto, Amaro, Juan M., Barrero, Alejandro F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10391625/
https://www.ncbi.nlm.nih.gov/pubmed/37338151
http://dx.doi.org/10.1021/acs.orglett.3c01470