Understanding heterogeneity of human bone marrow plasma cell maturation and survival pathways by single-cell analyses

Human bone marrow (BM) plasma cells are heterogeneous, ranging from newly arrived antibody-secreting cells (ASCs) to long-lived plasma cells (LLPCs). We provide single-cell transcriptional resolution of 17,347 BM ASCs from five healthy adults. Fifteen clusters are identified ranging from newly minte...

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Detalles Bibliográficos
Autores principales: Duan, Meixue, Nguyen, Doan C., Joyner, Chester J., Saney, Celia L., Tipton, Christopher M., Andrews, Joel, Lonial, Sagar, Kim, Caroline, Hentenaar, Ian, Kosters, Astrid, Ghosn, Eliver, Jackson, Annette, Knechtle, Stuart, Maruthamuthu, Stalinraja, Chandran, Sindhu, Martin, Tom, Rajalingam, Raja, Vincenti, Flavio, Breeden, Cynthia, Sanz, Ignacio, Gibson, Greg, Lee, F. Eun-Hyung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10391632/
https://www.ncbi.nlm.nih.gov/pubmed/37355988
http://dx.doi.org/10.1016/j.celrep.2023.112682

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10391632/
https://www.ncbi.nlm.nih.gov/pubmed/37355988
http://dx.doi.org/10.1016/j.celrep.2023.112682

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