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Efficacy and Tolerability of ALK/MET Combinations in Patients With ALK-Rearranged Lung Cancer With Acquired MET Amplification: A Retrospective Analysis

INTRODUCTION: MET amplification is a potentially actionable resistance mechanism in ALK-rearranged (ALK+) lung cancer. Studies describing treatment outcomes of this molecular subgroup are lacking. METHODS: We assembled a cohort of patients with ALK+ lung cancer and acquired MET amplification (identi...

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Detalles Bibliográficos
Autores principales: Dagogo-Jack, Ibiayi, Kiedrowski, Lesli A., Heist, Rebecca S., Lin, Jessica J., Meador, Catherine B., Krueger, Elizabeth A., Do, Andrew, Peterson, Jennifer, Sequist, Lecia V., Gainor, Justin F., Lennerz, Jochen K., Digumarthy, Subba R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10391652/
https://www.ncbi.nlm.nih.gov/pubmed/37533439
http://dx.doi.org/10.1016/j.jtocrr.2023.100534