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HILPDA is a lipotoxic marker in adipocytes that mediates the autocrine negative feedback regulation of triglyceride hydrolysis by fatty acids and alleviates cellular lipotoxic stress

BACKGROUND: Lipolysis is a key metabolic pathway in adipocytes that renders stored triglycerides available for use by other cells and tissues. Non-esterified fatty acids (NEFAs) are known to exert feedback inhibition on adipocyte lipolysis, but the underlying mechanisms have only partly been elucida...

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Detalles Bibliográficos
Autores principales: Deng, Lei, Wu, Shuangcheng Alivia, Qi, Ling, Kersten, Sander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10391665/
https://www.ncbi.nlm.nih.gov/pubmed/37422000
http://dx.doi.org/10.1016/j.molmet.2023.101773