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Microfluidic intestinal organoid-on-a-chip uncovers therapeutic targets by recapitulating oxygen dynamics of intestinal IR injury

Increasing evidence demonstrates that mammals have different reactions to hypoxia with varied oxygen dynamic patterns. It takes ∼24 h for tri-gas incubator to achieve steady cell hypoxia, which fails to recapitulate ultrafast oxygen dynamics of intestinal ischemia/reperfusion (IR) injury. Inspired f...

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Detalles Bibliográficos
Autores principales: Huang, Jinjian, Xu, Ziyan, Jiao, Jiao, Li, Zongan, Li, Sicheng, Liu, Ye, Li, Ze, Qu, Guiwen, Wu, Jie, Zhao, Yun, Chen, Kang, Li, Jieshou, Pan, Yichang, Wu, Xiuwen, Ren, Jianan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10391666/
https://www.ncbi.nlm.nih.gov/pubmed/37534235
http://dx.doi.org/10.1016/j.bioactmat.2023.07.001