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Robust induction of functional astrocytes using NGN2 expression in human pluripotent stem cells

Emerging evidence of species divergent features of astrocytes coupled with the relative inaccessibility of human brain tissue underscore the utility of human pluripotent stem cell (hPSC) technologies for the generation and study of human astrocytes. However, existing approaches for hPSC-astrocyte ge...

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Detalles Bibliográficos
Autores principales: Berryer, Martin H., Tegtmeyer, Matthew, Binan, Loïc, Valakh, Vera, Nathanson, Anna, Trendafilova, Darina, Crouse, Ethan, Klein, Jenny A., Meyer, Daniel, Pietiläinen, Olli, Rapino, Francesca, Farhi, Samouil L., Rubin, Lee L., McCarroll, Steven A., Nehme, Ralda, Barrett, Lindy E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10391684/
https://www.ncbi.nlm.nih.gov/pubmed/37534135
http://dx.doi.org/10.1016/j.isci.2023.106995