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Dephosphorylation of Six2Y129 protects tyrosine hydroxylase-positive cells in SNpc by regulating TEA domain 1 expression
Parkinson’s disease (PD) is a neurodegenerative disease characterized by selective loss of dopaminergic (DA) neurons in the substantia nigra pars compacta (SNpc). We recently reported that Six2 could reverse the degeneration of DA neurons in a dephosphorylation state. Here we further identified that...
Autores principales: | Zhang, Can-tang, Qin, Deng-li, Cao, Xia-yin, Kan, Jia-shuo, Huang, Xin-xing, Gao, Dian-shuai, Gao, Jin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10391717/ https://www.ncbi.nlm.nih.gov/pubmed/37534182 http://dx.doi.org/10.1016/j.isci.2023.107049 |
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