Microbial metabolite p-cresol inhibits gut hormone expression and regulates small intestinal transit in mice

p-cresol is a metabolite produced by microbial metabolism of aromatic amino acid tyrosine. p-cresol and its conjugated forms, p-cresyl sulfate and p-cresyl glucuronide, are uremic toxins that correlate positively with chronic kidney disease and diabetes pathogenesis. However, how p-cresol affects gu...

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Detalles Bibliográficos
Autores principales: Toft, Pernille Baumann, Vanslette, Amanda Marie, Trošt, Kajetan, Moritz, Thomas, Gillum, Matthew Paul, Bäckhed, Fredrik, Arora, Tulika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10391832/
https://www.ncbi.nlm.nih.gov/pubmed/37534214
http://dx.doi.org/10.3389/fendo.2023.1200391

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10391832/
https://www.ncbi.nlm.nih.gov/pubmed/37534214
http://dx.doi.org/10.3389/fendo.2023.1200391

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