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Microbial metabolite p-cresol inhibits gut hormone expression and regulates small intestinal transit in mice
p-cresol is a metabolite produced by microbial metabolism of aromatic amino acid tyrosine. p-cresol and its conjugated forms, p-cresyl sulfate and p-cresyl glucuronide, are uremic toxins that correlate positively with chronic kidney disease and diabetes pathogenesis. However, how p-cresol affects gu...
Autores principales: | Toft, Pernille Baumann, Vanslette, Amanda Marie, Trošt, Kajetan, Moritz, Thomas, Gillum, Matthew Paul, Bäckhed, Fredrik, Arora, Tulika |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10391832/ https://www.ncbi.nlm.nih.gov/pubmed/37534214 http://dx.doi.org/10.3389/fendo.2023.1200391 |
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