The antipsychotic medications aripiprazole, brexpiprazole and cariprazine are off-target respiratory chain complex I inhibitors

Antipsychotic drugs are the mainstay of treatment for schizophrenia and provide adjunct therapies for other prevalent psychiatric conditions, including bipolar disorder and major depressive disorder. However, they also induce debilitating extrapyramidal syndromes (EPS), such as Parkinsonism, in a si...

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Detalles Bibliográficos
Autores principales: Hardy, Rachel E., Chung, Injae, Yu, Yizhou, Loh, Samantha H. Y., Morone, Nobuhiro, Soleilhavoup, Clement, Travaglio, Marco, Serreli, Riccardo, Panman, Lia, Cain, Kelvin, Hirst, Judy, Martins, Luis M., MacFarlane, Marion, Pryde, Kenneth R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10391878/
https://www.ncbi.nlm.nih.gov/pubmed/37528429
http://dx.doi.org/10.1186/s13062-023-00375-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10391878/
https://www.ncbi.nlm.nih.gov/pubmed/37528429
http://dx.doi.org/10.1186/s13062-023-00375-9

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