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Colonic stem cells from normal tissues adjacent to tumor drive inflammation and fibrosis in colorectal cancer
BACKGROUND: In colorectal cancer (CRC), the normal tissue adjacent to tumor (NAT) communicates actively with the tumor. Adult stem cells from the colon play a crucial role in the development of the colonic epithelium. In the tumor microenvironment, however, it is unclear what changes have occurred i...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10391886/ https://www.ncbi.nlm.nih.gov/pubmed/37528407 http://dx.doi.org/10.1186/s12964-023-01140-1 |