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Inhibition of CDC20 potentiates anti-tumor immunity through facilitating GSDME-mediated pyroptosis in prostate cancer

BACKGROUND: Increasing evidence suggests that immunotherapy, especially immune checkpoint inhibitors (ICIs), has the potential to facilitate long-term survival in various cancer besides prostate cancer. Emerging evidence indicated that pyroptosis, an immunogenic form of cell death, could trigger an...

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Detalles Bibliográficos
Autores principales: Wu, Fei, Wang, Minglei, Zhong, Tao, Xiao, Changyan, Chen, Xiaozheng, Huang, Yiheng, Wu, Meng, Yu, Jinming, Chen, Dawei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10391908/
https://www.ncbi.nlm.nih.gov/pubmed/37528490
http://dx.doi.org/10.1186/s40164-023-00428-9