Differential effects of two phosphodiesterase 4 inhibitors against lipopolysaccharide-induced neuroinflammation in mice

BACKGROUND: Several phosphodiesterase 4 (PDE4) inhibitors have emerged as potential therapeutics for central nervous system (CNS) diseases. This study investigated the pharmacological effects of two selective PDE4 inhibitors, roflumilast and zatolmilast, against lipopolysaccharide-induced neuroinfla...

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Detalles Bibliográficos
Autores principales: Kang, Dong Ho, Ahn, Sunjoo, Chae, Jung Woo, Song, Jin Sook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10391911/
https://www.ncbi.nlm.nih.gov/pubmed/37525115
http://dx.doi.org/10.1186/s12868-023-00810-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10391911/
https://www.ncbi.nlm.nih.gov/pubmed/37525115
http://dx.doi.org/10.1186/s12868-023-00810-7

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