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Vamorolone improves Becker muscular dystrophy and increases dystrophin protein in bmx model mice

There is no approved therapy for Becker muscular dystrophy (BMD), a genetic muscle disease caused by in-frame dystrophin deletions. We previously developed the dissociative corticosteroid vamorolone for treatment of the allelic, dystrophin-null disease Duchenne muscular dystrophy. We hypothesize vam...

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Detalles Bibliográficos
Autores principales: McCormack, Nikki M., Nguyen, Nhu Y., Tully, Christopher B., Oliver, Trinitee, Fiorillo, Alyson A., Heier, Christopher R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10391915/
https://www.ncbi.nlm.nih.gov/pubmed/37534133
http://dx.doi.org/10.1016/j.isci.2023.107161