Inhibition of NETosis via PAD4 alleviated inflammation in giant cell myocarditis

Giant cell myocarditis (GCM) is a rare, usually rapidly progressive, and potentially fatal disease. Detailed inflammatory responses remain unknown, in particular the formation of multinucleate giant cells. We performed single-cell RNA sequencing analysis on 15,714 Cd45(+) cells extracted from the he...

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Detalles Bibliográficos
Autores principales: Hu, Zhan, Hua, Xiumeng, Mo, Xiuxue, Chang, Yuan, Chen, Xiao, Xu, Zhenyu, Tao, Mengtao, Hu, Gang, Song, Jiangping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10391931/
https://www.ncbi.nlm.nih.gov/pubmed/37534129
http://dx.doi.org/10.1016/j.isci.2023.107162

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10391931/
https://www.ncbi.nlm.nih.gov/pubmed/37534129
http://dx.doi.org/10.1016/j.isci.2023.107162

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