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Inhibition of NETosis via PAD4 alleviated inflammation in giant cell myocarditis
Giant cell myocarditis (GCM) is a rare, usually rapidly progressive, and potentially fatal disease. Detailed inflammatory responses remain unknown, in particular the formation of multinucleate giant cells. We performed single-cell RNA sequencing analysis on 15,714 Cd45(+) cells extracted from the he...
Autores principales: | Hu, Zhan, Hua, Xiumeng, Mo, Xiuxue, Chang, Yuan, Chen, Xiao, Xu, Zhenyu, Tao, Mengtao, Hu, Gang, Song, Jiangping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10391931/ https://www.ncbi.nlm.nih.gov/pubmed/37534129 http://dx.doi.org/10.1016/j.isci.2023.107162 |
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