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Role of SH3GLB1 in the regulation of CD133 expression in GBM cells

BACKGROUND: Glioblastoma (GBM), a malignant brain tumor, has poor survival outcomes due to recurrence or drug resistance. We found that SH3GLB1 is a crucial factor for cells to evade temozolomide (TMZ) cytotoxicity through autophagy-mediated oxidative phosphorylation, which is associated with CD133...

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Detalles Bibliográficos
Autores principales: Chien, Chia-Hung, Lai, Chien-Cheng, Chuang, Jian-Ying, Chu, Jui-Mei, Liu, Chan-Chuan, Chang, Kwang-Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10391956/
https://www.ncbi.nlm.nih.gov/pubmed/37525108
http://dx.doi.org/10.1186/s12885-023-11211-8