Terminally exhausted CD8(+) T cells contribute to age-dependent severity of respiratory virus infection

BACKGROUND: Lower respiratory infections are a leading cause of severe morbidity and mortality among older adults. Despite ubiquitous exposure to common respiratory pathogens throughout life and near universal seropositivity, antibodies fail to effectively protect the elderly. Therefore, we hypothes...

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Detalles Bibliográficos
Autores principales: Parks, Olivia B., Eddens, Taylor, Sojati, Jorna, Lan, Jie, Zhang, Yu, Oury, Tim D., Ramsey, Manda, Erickson, John J., Byersdorfer, Craig A., Williams, John V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10391960/
https://www.ncbi.nlm.nih.gov/pubmed/37528458
http://dx.doi.org/10.1186/s12979-023-00365-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10391960/
https://www.ncbi.nlm.nih.gov/pubmed/37528458
http://dx.doi.org/10.1186/s12979-023-00365-5

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