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Genetic impacts on DNA methylation help elucidate regulatory genomic processes

BACKGROUND: Pinpointing genetic impacts on DNA methylation can improve our understanding of pathways that underlie gene regulation and disease risk. RESULTS: We report heritability and methylation quantitative trait locus (meQTL) analysis at 724,499 CpGs profiled with the Illumina Infinium Methylati...

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Detalles Bibliográficos
Autores principales: Villicaña, Sergio, Castillo-Fernandez, Juan, Hannon, Eilis, Christiansen, Colette, Tsai, Pei-Chien, Maddock, Jane, Kuh, Diana, Suderman, Matthew, Power, Christine, Relton, Caroline, Ploubidis, George, Wong, Andrew, Hardy, Rebecca, Goodman, Alissa, Ong, Ken K., Bell, Jordana T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10391992/
https://www.ncbi.nlm.nih.gov/pubmed/37525248
http://dx.doi.org/10.1186/s13059-023-03011-x