Cryo‐EM structures of tau filaments from SH‐SY5Y cells seeded with brain extracts from cases of Alzheimer's disease and corticobasal degeneration

The formation of amyloid filaments through templated seeding is believed to underlie the propagation of pathology in most human neurodegenerative diseases. A widely used model system to study this process is to seed amyloid filament formation in cultured cells using human brain extracts. Here, we re...

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Detalles Bibliográficos
Autores principales: Tarutani, Airi, Lövestam, Sofia, Zhang, Xianjun, Kotecha, Abhay, Robinson, Andrew C., Mann, David M. A., Saito, Yuko, Murayama, Shigeo, Tomita, Taisuke, Goedert, Michel, Scheres, Sjors H. W., Hasegawa, Masato
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10392052/
https://www.ncbi.nlm.nih.gov/pubmed/37337995
http://dx.doi.org/10.1002/2211-5463.13657

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10392052/
https://www.ncbi.nlm.nih.gov/pubmed/37337995
http://dx.doi.org/10.1002/2211-5463.13657

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