Cargando…

Cryo‐EM structures of tau filaments from SH‐SY5Y cells seeded with brain extracts from cases of Alzheimer's disease and corticobasal degeneration

The formation of amyloid filaments through templated seeding is believed to underlie the propagation of pathology in most human neurodegenerative diseases. A widely used model system to study this process is to seed amyloid filament formation in cultured cells using human brain extracts. Here, we re...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tarutani, Airi, Lövestam, Sofia, Zhang, Xianjun, Kotecha, Abhay, Robinson, Andrew C., Mann, David M. A., Saito, Yuko, Murayama, Shigeo, Tomita, Taisuke, Goedert, Michel, Scheres, Sjors H. W., Hasegawa, Masato
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2023
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10392052/ https://www.ncbi.nlm.nih.gov/pubmed/37337995 http://dx.doi.org/10.1002/2211-5463.13657

Ejemplares similares

Novel tau filament fold in corticobasal degeneration
por: Zhang, Wenjuan, et al.
Publicado: (2020)

Seeded assembly in vitro does not replicate the structures of α‐synuclein filaments from multiple system atrophy
por: Lövestam, Sofia, et al.
Publicado: (2021)

High-throughput cryo-EM structure determination of amyloids
por: Lövestam, Sofia, et al.
Publicado: (2022)

Cryo-EM Structures of Chronic Traumatic Encephalopathy Tau Filaments with PET Ligand Flortaucipir
por: Shi, Yang, et al.
Publicado: (2023)

Assembly of recombinant tau into filaments identical to those of Alzheimer’s disease and chronic traumatic encephalopathy
por: Lövestam, Sofia, et al.
Publicado: (2022)

Cryo-EM structures of Tau filaments from Alzheimer’s disease brain
por: Fitzpatrick, Anthony W.P., et al.
Publicado: (2017)

Cryo-EM structures of tau filaments from the brains of mice transgenic for human mutant P301S Tau
por: Schweighauser, Manuel, et al.
Publicado: (2023)

Cryo-EM structures of amyloid-β filaments with the Arctic mutation (E22G) from human and mouse brains
por: Yang, Yang, et al.
Publicado: (2023)

A Bayesian View on Cryo-EM Structure Determination
por: Scheres, Sjors H.W.
Publicado: (2012)

Cryo-EM structures of Aβ40 filaments from the leptomeninges of individuals with Alzheimer’s disease and cerebral amyloid angiopathy
por: Yang, Yang, et al.
Publicado: (2023)

Cryo-EM structures of τ filaments from human brain
por: Goedert, Michel
Publicado: (2021)

Beam-induced motion correction for sub-megadalton cryo-EM particles
por: Scheres, Sjors HW
Publicado: (2014)

Cryo-EM structures of tau filaments from Alzheimer’s disease with PET ligand APN-1607
por: Shi, Yang, et al.
Publicado: (2021)

RELION: Implementation of a Bayesian approach to cryo-EM structure determination
por: Scheres, Sjors H.W.
Publicado: (2012)

Semi-automated selection of cryo-EM particles in RELION-1.3
por: Scheres, Sjors H.W.
Publicado: (2015)

Correction to: Cryo-EM structures of tau filaments from Alzheimer’s disease with PET ligand APN-1607
por: Shi, Yang, et al.
Publicado: (2021)

New SNCA mutation and structures of α-synuclein filaments from juvenile-onset synucleinopathy
por: Yang, Yang, et al.
Publicado: (2023)

Cryo-EM at ACA 2022
por: Subramaniam, Sriram, et al.
Publicado: (2022)

Age-dependent formation of TMEM106B amyloid filaments in human brains
por: Schweighauser, Manuel, et al.
Publicado: (2022)

Structures of α-synuclein filaments from human brains with Lewy pathology
por: Yang, Yang, et al.
Publicado: (2022)

Accelerated cryo-EM structure determination with parallelisation using GPUs in RELION-2
por: Kimanius, Dari, et al.
Publicado: (2016)

Automated model building and protein identification in cryo-EM maps
por: Jamali, Kiarash, et al.
Publicado: (2023)

A Bayesian approach to beam-induced motion correction in cryo-EM single-particle analysis
por: Zivanov, Jasenko, et al.
Publicado: (2019)

Characterisation of molecular motions in cryo-EM single-particle data by multi-body refinement in RELION
por: Nakane, Takanori, et al.
Publicado: (2018)

Ribosome structures to near-atomic resolution from thirty thousand cryo-EM particles
por: Bai, Xiao-chen, et al.
Publicado: (2013)

Estimation of high-order aberrations and anisotropic magnification from cryo-EM data sets in RELION-3.1
por: Zivanov, Jasenko, et al.
Publicado: (2020)

New tools for automated cryo-EM single-particle analysis in RELION-4.0
por: Kimanius, Dari, et al.
Publicado: (2021)

Cryo-EM of dynein microtubule-binding domains shows how an axonemal dynein distorts the microtubule
por: Lacey, Samuel E, et al.
Publicado: (2019)

Exploiting prior knowledge about biological macromolecules in cryo-EM structure determination
por: Kimanius, Dari, et al.
Publicado: (2021)

New tools for automated high-resolution cryo-EM structure determination in RELION-3
por: Zivanov, Jasenko, et al.
Publicado: (2018)

Cryo-EM structure of a separase-securin complex at near-atomic resolution
por: Boland, Andreas, et al.
Publicado: (2017)

Cryo-EM structure of the complete inner kinetochore of the budding yeast point centromere
por: Dendooven, Tom, et al.
Publicado: (2023)

cryo-EM structures of the E. coli replicative DNA polymerase reveal its dynamic interactions with the DNA sliding clamp, exonuclease and τ
por: Fernandez-Leiro, Rafael, et al.
Publicado: (2015)

Cryo-EM structure of the Plasmodium falciparum 80S ribosome bound to the anti-protozoan drug emetine
por: Wong, Wilson, et al.
Publicado: (2014)

CryoEM structure of MxB reveals a novel oligomerization interface critical for HIV restriction
por: Alvarez, Frances J. D., et al.
Publicado: (2017)

Cryo-EM structure of an active bacterial TIR–STING filament complex
por: Morehouse, Benjamin R., et al.
Publicado: (2022)

Heparin-induced tau filaments are polymorphic and differ from those in Alzheimer’s and Pick’s diseases
por: Zhang, Wenjuan, et al.
Publicado: (2019)

Cryo-EM structures of the eukaryotic replicative helicase bound to a translocation substrate
por: Abid Ali, Ferdos, et al.
Publicado: (2016)

Distinct tau folds initiate templated seeding and alter the post-translational modification profile
por: Tarutani, Airi, et al.
Publicado: (2023)

Potent prion-like behaviors of pathogenic α-synuclein and evaluation of inactivation methods
por: Tarutani, Airi, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_lvcj8p2qi4535e4rbn66rt3kc3