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A novel biologically hierarchical hydrogel with osteoblast precursor‐targeting extracellular vesicles ameliorates bone loss in vivo via the sequential action of antagomiR‐200b‐3p and antagomiR‐130b‐3p

Osteoporotic fracture is a major health problem plaguing the ageing society, and improving its treatment is an urgent challenge. How to ameliorate bone loss determines the recovery of such fractures. Extracellular vesicle (EV)‐loaded hydrogel has the capacity to treat osteoporotic fractures due to i...

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Detalles Bibliográficos
Autores principales: Dai, Hanhao, Yu, Yunlong, Han, Junyong, Luo, Jun, Song, Chao, Deng, Zhibo, Wu, Yijing, Ke, Dianshan, Xu, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10392057/
https://www.ncbi.nlm.nih.gov/pubmed/36786008
http://dx.doi.org/10.1111/cpr.13426