Dexamethasone induces p21(cip1/waf1) expression via FoxO3a independently of the Lamin A/C‐HDAC2 interaction in Ataxia Telangiectasia

Ataxia‐Telangiectasia (A‐T) is a very rare autosomal recessive multisystemic disorder which to date is still uncurable. The use of glucocorticoid analogs, such as dexamethasone (dex), can improve neurological symptoms in patients, but the molecular mechanism of action of these analogs remains unclea...

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Detalles Bibliográficos
Autores principales: Ricci, Anastasia, Biancucci, Federica, Morganti, Gianluca, Magnani, Mauro, Menotta, Michele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10392059/
https://www.ncbi.nlm.nih.gov/pubmed/37345209
http://dx.doi.org/10.1002/2211-5463.13663

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10392059/
https://www.ncbi.nlm.nih.gov/pubmed/37345209
http://dx.doi.org/10.1002/2211-5463.13663

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