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Dexamethasone induces p21(cip1/waf1) expression via FoxO3a independently of the Lamin A/C‐HDAC2 interaction in Ataxia Telangiectasia
Ataxia‐Telangiectasia (A‐T) is a very rare autosomal recessive multisystemic disorder which to date is still uncurable. The use of glucocorticoid analogs, such as dexamethasone (dex), can improve neurological symptoms in patients, but the molecular mechanism of action of these analogs remains unclea...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10392059/ https://www.ncbi.nlm.nih.gov/pubmed/37345209 http://dx.doi.org/10.1002/2211-5463.13663 |