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OGG1 aggravates renal ischemia–reperfusion injury by repressing PINK1‐mediated mitophagy

Renal ischemia–reperfusion injury (IRI) is mainly responsible for acute kidney injury for which there is no effective therapy. Accumulating evidence has indicated the important role of mitophagy in mitochondrial homeostasis under stress. OGG1 (8‐oxoguanine DNA glycosylase) is known for functions in...

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Detalles Bibliográficos
Autores principales: Zhao, Fan, Zhu, Jiefu, Zhang, Mingjiao, Luo, Yanwen, Li, Yuzhen, Shi, Lang, Huang, Jing, Shadekejiang, Halinuer, Dong, Shengyu, Wu, Xiongfei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10392062/
https://www.ncbi.nlm.nih.gov/pubmed/36788635
http://dx.doi.org/10.1111/cpr.13418