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In-Depth Mass Spectrometry Analysis Reveals the Plasma Proteomic and N-Glycoproteomic Impact of an Amish-Enriched Cardioprotective Variant in B4GALT1

B4GALT1 encodes β-1,4-galactosyltransferase 1, an enzyme that plays a major role in glycan synthesis in the Golgi apparatus by catalyzing the addition of terminal galactose. Studies increasingly suggest that B4GALT1 may be involved in the regulation of lipid metabolism pathways. Recently, we discove...

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Detalles Bibliográficos
Autores principales: Zhao, Yunlong, Nayak, Shruti, Raidas, Shivkumar, Guo, Lili, Della Gatta, Giusy, Koppolu, Sujeethraj, Halasz, Gabor, Montasser, May E., Shuldiner, Alan R., Mao, Yuan, Li, Ning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10392133/
https://www.ncbi.nlm.nih.gov/pubmed/37328064
http://dx.doi.org/10.1016/j.mcpro.2023.100595