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Facioscapulohumeral Muscular Dystrophy is Associated With Altered Myoblast Proteome Dynamics

Proteomic studies in facioscapulohumeral muscular dystrophy (FSHD) could offer new insight into disease mechanisms underpinned by post-transcriptional processes. We used stable isotope (deuterium oxide; D(2)O) labeling and peptide mass spectrometry to investigate the abundance and turnover rates of...

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Detalles Bibliográficos
Autores principales: Nishimura, Yusuke, Bittel, Adam J., Stead, Connor A., Chen, Yi-Wen, Burniston, Jatin G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10392138/
https://www.ncbi.nlm.nih.gov/pubmed/37353005
http://dx.doi.org/10.1016/j.mcpro.2023.100605