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Poster 113: Epigenetic Regulation of PPARγ Rescues Articular Chondrocytes from Catabolic State Suggesting PPARγ as a Potential Target to Slow Down Progression of OA in Hip FAI

OBJECTIVES: Hip Femoroacetabular impingement (FAI) has a high prevalence of chondral lesions, and the severity of chondral damage is associated with an increased risk of postoperative OA progression, but the mechanisms of cartilage degeneration in OA progression remains unclear. Peroxisome prolifera...

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Detalles Bibliográficos
Autores principales: Kamenaga, Tomoyuki, Shen, Jie, Wu, May, Brophy, Robert, O’Keefe, Regis, Clohisy, John, Pascual-Garrido, Cecilia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10392545/
http://dx.doi.org/10.1177/2325967123S00103