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Dissecting Detergent-Insoluble Proteome in Alzheimer's Disease by TMTc-Corrected Quantitative Mass Spectrometry

Protein aggregation of amyloid-β peptides and tau are pathological hallmarks of Alzheimer's disease (AD), which are often resistant to detergent extraction and thus enriched in the insoluble proteome. However, additional proteins that coaccumulate in the detergent-insoluble AD brain proteome re...

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Detalles Bibliográficos
Autores principales: Zaman, Masihuz, Fu, Yingxue, Chen, Ping-Chung, Sun, Huan, Yang, Shu, Wu, Zhiping, Wang, Zhen, Poudel, Suresh, Serrano, Geidy E., Beach, Thomas G., Li, Ling, Wang, Xusheng, Peng, Junmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10392608/
https://www.ncbi.nlm.nih.gov/pubmed/37356496
http://dx.doi.org/10.1016/j.mcpro.2023.100608