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Homologous basic helix–loop–helix transcription factors induce distinct deformations of torsionally-stressed DNA: a potential transcription regulation mechanism

Changing torsional restraints on DNA is essential for the regulation of transcription. Torsional stress, introduced by RNA polymerase, can propagate along chromatin facilitating topological transitions and modulating the specific binding of transcription factors (TFs) to DNA. Despite the importance,...

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Detalles Bibliográficos
Autores principales: Hörberg, Johanna, Moreau, Kevin, Reymer, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10392670/
https://www.ncbi.nlm.nih.gov/pubmed/37529292
http://dx.doi.org/10.1017/qrd.2022.5