Abnormal methylation in the NDUFA13 gene promoter of breast cancer cells breaks the cooperative DNA recognition by transcription factors

Selective DNA binding by transcription factors (TFs) is crucial for the correct regulation of DNA transcription. In healthy cells, promoters of active genes are hypomethylated. A single CpG methylation within a TF response element (RE) may change the binding preferences of the protein, thus causing...

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Detalles Bibliográficos
Autores principales: Hörberg, Johanna, Hallbäck, Björn, Moreau, Kevin, Reymer, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10392677/
https://www.ncbi.nlm.nih.gov/pubmed/37529293
http://dx.doi.org/10.1017/qrd.2022.21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10392677/
https://www.ncbi.nlm.nih.gov/pubmed/37529293
http://dx.doi.org/10.1017/qrd.2022.21

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