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Computer-aided comprehensive explorations of RNA structural polymorphism through complementary simulation methods

While RNA folding was originally seen as a simple problem to solve, it has been shown that the promiscuous interactions of the nucleobases result in structural polymorphism, with several competing structures generally observed for non-coding RNA. This inherent complexity limits our understanding of...

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Detalles Bibliográficos
Autores principales: Röder, Konstantin, Stirnemann, Guillaume, Faccioli, Pietro, Pasquali, Samuela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10392686/
https://www.ncbi.nlm.nih.gov/pubmed/37529277
http://dx.doi.org/10.1017/qrd.2022.19